Table 1.

Nuclear pore complex numbers vary between different species and cell types.

Cell type/line	Experimental condition	NPCs/nucleus	Imaging method	Reference
Rat heart muscle cells	Fetal (E14.5)	1,900	CM, STORM	[33]
	Neonatal (P2)	1,000
	Adult (P60)	700
Rat heart muscle cells	Neonatal (P2)		CM	[33]
	Mononucleated	1,300
	Binucleated	900
	Adult (P60)
	Mononucleated	800
	Binucleated	560
Mouse heart muscle cells	Neonatal (P2)	1,500	STORM	[33]
African frog heart cells	NA	3,500	EM	[65]
Northern Crested newt heart cells	NA	12,000	EM	[65]
Eastern newt lens	NA	16,000	EM	[65]
Rat liver	6 weeks	450	SIM	[71]
	6 months	450
	13 months	530
	2 years	450
Rat brain	6 weeks	430	SIM	[71]
	6 months	380
	13 months	330
	2 years	290
Normal rat kidney (NRK)	Early G1	2,000	Live CM	[102]
	Late G2	2,800
Human T-lymphocytes	Baseline	250–290	EM	[78]
	After stimulation	~1,800
HeLa	Baseline (G1)	2,000	EM	[78]
	End of S-phase	4,000
U2OS	NA	3,000–5,000	SIM	[56]
Yeast	NA	100	EM	[65]

Note: CM, confocal microscopy; STORM, stochastic optical reconstruction microscopy; EM, electron microscopy of freeze-fracture replicas; SIM, structured illumination microscopy.