Table 1.
Inclusion criteria | Arm A | Arm B |
---|---|---|
Age 18–70 years | Yes | Yes |
Traumatic SCI | Yes | Yes |
Atraumatic sudden onset SCI | No | Yes |
Within 10 days post-SCI | Yes | No |
History of recurrent UTI | No | Yes |
Exclusion criteria | ||
Admission to hospital outside Western Australia | Yes | No |
Inability to commence HA + CS Within 10 days of SCI | Yes | No |
Spontaneous voiding | Yes | Yes |
Bladder/urethral trauma on Admission | Yes | Yes |
Bladder cancer/other bladder Pathology | Yes | Yes |
Known hypersensitivity to HA or CS | Yes | Yes |
UTI before commencing Study intervention | Yes | No |
Current pregnancy | Yes | Yes |
History of neurological disorder | Yes | Yes |
Inability to provide consent | Yes | Yes |
History of autonomic Dysreflexia with urological procedures | No | Yes |
CS = chrondroitin sulphate, HA = hyaluronic acid, SCI = spinal cord injury, UTI = urinary tract infection.