Table 3.

Adverse events following intravesical hyaluronic acid + chondroitin sulphate (HA + CS).

Timing of AE	Description	Severity	Relationship to HA + CS	Outcome
<24 h	Nausea/chills/headache	Mild	Unlikely	Resolved
<24 h	Headache/fatigue	Mild	Unlikely	Resolved
<24 h	Bladder spasms	Mild	Suspected	Resolved
<24 h	Cloudy urine/ bladder pain	Mild	Suspected	Resolved
<24 h	Cloudy urine/sediment	Mild	Suspected	Resolved
<24 h	Cloudy urine	Mild	Suspected	Resolved
<24 h	Sediment in urine	Mild	Suspected	Resolved
<24 h	Sediment in urine	Mild	Suspected	Resolved
<7 days	UTI	Mild	Suspected	Antibiotics
<7 days	Bladder pain/cloudy urine	Mild	Unlikely	Resolved
<7 days	Bladder pain	Mild	Unlikely	Resolved
>7 days	Chest infection	Moderate	Unlikely	Antibiotics
>7 days	Infected SPC site	Mild	Unlikely	Resolved

AE = adverse event, SPC = suprapubic catheter, UTI = urinary tract infection.