TABLE 4.
Characteristics of infective endocarditis subjects according to blood culture results
| Characteristic | Total no. | No. by blood culture result: |
|
|---|---|---|---|
| Positive (n = 22) | Negative (n = 18) | ||
| 16S rRNA gene PCR/sequencing | |||
| Positive | 30 | 19a | 11 |
| Negative | 10 | 3 | 7 |
| Antibiotic treatment prior to blood culture | 9 | 1 | 8 |
| Known microbiology | 35 | 22 | 13 |
| Streptococcus species | 10 | 8 | 2 |
| Streptococcus salivarius group | 3 | 3 | 0 |
| Streptococcus sanguinis | 3 | 2 | 1 |
| Streptococcus mitis group | 2 | 1 | 1 |
| Streptococcus agalactiae | 1 | 1 | 0 |
| Streptococcus mutans | 1 | 1 | 0 |
| Staphylococcus species | 8 | 7 | 1 |
| Staphylococcus epidermidis | 4 | 3a | 1 |
| Staphylococcus aureus complex | 3 | 3 | 0 |
| Staphylococcus lugdunensis | 1 | 1 | 0 |
| Enterococcus faecalis | 2 | 2 | 0 |
| Cutibacterium acnes | 5 | 0 | 5 |
| Bartonella species | 3 | 0 | 3 |
| Other | 7 | 5b | 2c |
| Unknown microbiology | 5 | 0 | 5 |
a
Results of the two tests were identical except in one case in which Staphylococcus epidermidis was found in blood culture and Pseudomonas aeruginosa was detected by 16S rRNA gene PCR/sequencing and valve tissue culture.
b
One case each involving Cardiobacterium hominis, Corynebacterium amycolatum, Granulicatella adiacens, Mycobacterium avium complex, and Parvimonas micra.
c
One case each involving Haemophilus parainfluenzae and Histoplasma capsulatum.