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. 2023 Aug 24;381(2257):20230130. doi: 10.1098/rsta.2023.0130

Table 3.

GRADE assessment of the included references—factors that can reduce quality: domain 1 limitations in study design or execution; domain 2 inconsistency of results; domain 3 indirectness of evidence; domain 4 imprecision; domain 5 publication bias; factors that can increase the quality: domain 6 large magnitude of effect; domain 7 residual confounding; domain 8 dose–response gradient. Assessment –assessed down 1 or 2 levels; –assessed up 1 or 2 levels; - –no effect.

factors that can reduce quality factors increase the quality
study domain 1 domain 2 domain 3 domain 4 domain 5 domain 6 domain 7 domain 8
ventilation 2 2 1 2
air cleaning
devices 2 2 1 2
occupancy 2 2 1 2
disinfection 2 1 2 2