Table 3.

Causal effect of NAFLD on falling risk using genetic variant randomization in different MR methods.

Exposure	Outcome	Method	No. of SNP	OR (95% CI)	95% CI	P
NAFLD	Falling risk	IVW	5	0.9912	0.9412-1.0440	0.740
		MR Egger	5	1.0211	0.8865-1.1763	0.791
		Weighted median	5	0.9987	0.9681-1.0301	0.932
		Simple mode	5	0.9949	0.9521-1.0396	0.831
		Weighted mode	5	0.9964	0.9613-1.0327	0.852
MR Egger: Cochran’s Q= 14.341, P= 0.002
IVW: Cochran’s Q= 15.315, P= 0.004
MR-Egger intercept= -0.006, P= 0.682
MR-PRESSO global test= 0.756

No outlier was observed in the MR-PRESSO analysis in MR analysis in NAFLD and fractures. CI, confidence interval; MR, Mendelian randomization; IVW, inverse-variance weighted; NAFLD, non-alcoholic fatty liver disease.