Table 1.
Participant data from randomized crossover study of sertraline
| Placebo | Sertraline | P value | |
|---|---|---|---|
| Sex | 9 females, 6 males | ||
| Age (years) | 24.7 ± 1.0 | 24.6 ± 1.0 | 0.568 |
| Weight (kg) | 65.0 ± 2.4 | 64.1 ± 2.2 | 0.029 |
| Height (m) | 1.70 ± 0.02 | 1.70 ± 0.02 | 0.065 |
| BMI (kg m−2) | 22.4 ± 0.5 | 22.0 ± 0.4 | 0.005 |
| Fat mass (kg) | 13.9 ± 1.4 | 11.9 ± 1.1 | 0.008 |
| Fat mass (%) | 19.9 ± 1.7 | 20.0 ± 2.3 | 0.960 |
| Systolic blood pressure (mmHg) | 127.1 ± 4.3 | 129.7 ± 5.0 | 0.492 |
| Diastolic blood pressure (mmHg) | 76.9 ± 3.0 | 76.1 ± 3.4 | 0.814 |
| Outdoor temperature (°C) | 6.3 ± 1.0 | 8.1 ± 1.2 | 0.266 |
| Warm room temperature (°C) | 23.3 ± 0.2 | 23.6 ± 0.2 | 0.294 |
| Cold room temperature (°C) | 16.7 ± 0.1 | 16.6 ± 0.1 | 0.267 |
Data are mean ± s.e.m. for all 15 participants. Outdoor temperature was measured at 10 a.m. on the morning of each study visit. The outdoor, warm and cold room temperatures were similar on both sertraline and placebo phases. Data were analysed using the paired t-test and significant P values are given in bold.