Extended Data Table 3.

Patient characteristics with detectable ¹⁸F-FDG uptake by BAT

Data are mean ± SEM. Anthropometric and biochemical data from patients who attended the Royal Infirmary of Edinburgh to undergo PET/CT scanning as part of their diagnostic pathway. All patients received either 370MBq or 4MBq/Kg of ¹⁸F-FDG 60 minutes prior to undergoing PET/CT scanning of their body. Patients were kept in a room at 20-21˚C prior to and following the ¹⁸F-FDG injection until the PET/CT scan was performed. Patients were divided into those with (BAT-positive) and without (BAT-negative) detectable ¹⁸F-FDG uptake by BAT. Data were analysed by unpaired t test, Mann Whitney U test or by Chi-squared test. Historical ambient temperature data were obtained from the Met Office Leuchars station which is situated closest to Edinburgh, Scotland, United Kingdom (https://www.metoffice.gov.uk/pub/data/weather/uk/climate/stationdata/leucharsdata.txt).*P = 0.042, **P = 0.002, ***P < 0.001 vs BAT negative group. Beta-blocker use tended (P = 0.07) to be associated with the BAT negative group.