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. 2023 Jun 18;11(3):343–360. doi: 10.1007/s40487-023-00234-7

Table 3.

Biomarker turnaround time in days by testing method within 6 months of diagnosis

Method Biomarker tests, n Mean Min 25% Median 75% Max
FISH 975 23.6 3 12 16 25 151
IHC 511 22.2 0 7 9 22 163
Mutation-specific IHC 6 13.8 7 8 10 12 36
NGS 2179 41.5 0 16 30 50.5 163
PCR 551 23.1 0 12 17 28 114
RNA sequencing 78 64.2 24 36 59 68.75 163
Sanger sequencing 403 14.8 6 9 11 14 138
Unspecified 77 37.8 0 13 20 29 152

Turnaround time is defined as the days elapsed from the date that the specimen was received/collected to the date of the test result. The distribution of turnaround times is restricted to those between 0 and 182 days. We excluded 49 out of 746 patients who received at least one biomarker test due to negative turnaround times or whose turnaround times were greater than 182 days

FISH fluorescence in situ hybridization, IHC immunohistochemistry, Max maximum, Min minimum, NGS next-generation sequencing, PCR polymerase chain reaction, RNA ribonucleic acid