Skip to main content
. 2023 Feb 2;108(5):478–484. doi: 10.1136/archdischild-2022-324977

Table 2.

Pathogen distribution in 582 late-onset sepsis (LOS) episodes and LOS-attributable mortality in 493 very preterm infants

Culture-positive LOS episodes
n=582 (%*)
LOS attributable death in
493 patients with a positive blood culture (%†)
Gram positive bacteria, excl. CoNS 183 (31.4) 7/163 (4.3)
Staphylococcus aureus 89 (15.1) 2 (2.2)
 Group B streptococcus 55 (9.5) 2 (3.6)
Enteroccocus spp. 24 (4.1) 2 (8.3)
Bacillus spp. 4 (0.7) 1 (2.5)
 Other 11 (1.9) 0 (0)
CoNS 282 (48.5) 9/224 (4.0)
Gram-negative bacteria 105 (18.0) 15/95 (15.8)
Escherichia coli 49 (8.4) 7 (14)
Klebsiella spp. 26 (4.5) 5 (19.2)
Enterobacter spp. 18 (3.1) 1 (5.6)
Serratia spp. 4 (0.7) 0 (0)
 Other 4 (0.7) 0 (0)
Salmonella spp. 2 (0.3) 1 (50)
Pseudomonas spp. 1 (0.2) 1 (100)
Acinetobacter spp. 1 (0.2) 0 (0)
Candida spp. 11 (1.9) 0/11 (0)
Other 1 (0.2) 0 (0)
Total 582 31/493 (6.3)

LOS attributable death was defined as death within 7 days of positive blood culture.

* Percentage of all LOS cases.

†Percentage infants in each pathogen category.

‡Only one out of 89 S. aureus cases was methicillin resistant.

CoNS, coagulase-negative staphylococci.