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. 2023 Aug 23;13:13770. doi: 10.1038/s41598-023-40300-8

Table 3.

Descriptive statistics of all observations of 7176 non-diabetic Japanese citizens of Zentsuji city stratified by HbA1c category with missing values completed by multiple imputation method (1998–2022).

HbA1c category
 < 5.0% 5.0–5.4% 5.5–5.9% 6.0–6.4% Total
Failure PY IR* Failure PY IR* Failure PY IR* Failure PY IR* Failure PY IR*
Time at risk
 Total 4441.2 19,532.1 26,026.6 5604.5 55,604.4
 Minimum 0.63 0.48 0.34 0.54 0.34
 Maximum 22.7 23.9 24.0 21.3 24.1
 Mean 3.76 4.76 5.44 3.66 7.75
 Median 2.08 3.10 4.01 2.13 6.11
 Failure 129 779 1210 256 2374
 IRa 29.0 39.9 46.5 45.7 42.7
Variables
 Sex
  Female 63 2743.3 23.0 471 12,051.7 39.1 722 16,286.7 44.3 169 3499.7 48.3 1425 34,581.4 41.2
  Male 66 1697.9 38.9 308 7480.4 41.2 488 9739.9 50.1 87 2104.8 41.3 949 21,023.0 45.1
 Age category
  34–59 28 2516.1 11.1 174 7770.6 22.4 197 7204.5 27.3 28 1062.6 26.4 427 18,553.8 23.0
  60–69 40 1009.9 39.6 235 6223.7 37.8 409 9793.1 41.8 95 2302.9 41.3 779 19,329.6 40.3
    ≥ 70 61 915.2 66.7 370 5537.8 66.8 604 9029.0 66.9 133 2239.0 59.4 1168 17,721.0 65.9
 BMI category
  Normal 100.0 3727.2 26.8 608.0 15,893.8 38.3 855.0 19,587.1 43.7 159.0 3660.6 43.4 1722.0 42,868.7 40.2
  Overweight or obeseb 29.0 714.0 40.6 171.0 3638.3 47.0 355.0 6439.5 55.1 97.0 1943.9 49.9 652.0 12,735.7 51.2
 Self-reported drinking status
  Nondrinker 62.7 2338.2 26.8 478.9 11,171.6 42.9 769.2 15,849.7 48.5 171.0 3575.9 47.8 1481.7 32,935.4 45.0
  Drinker 66.4 2103.0 31.5 300.1 8360.5 35.9 440.8 10,176.9 43.3 85.0 2028.6 41.9 892.3 22,669.0 39.4
 Self-reported smoking status
  Nonsmoker 104.3 3416.6 30.5 658.7 15,816.1 41.6 1022.6 21,799.5 46.9 219.2 4741.9 46.2 2004.8 45,774.1 43.8
  Smoker 24.8 1024.6 24.2 120.3 3716.0 32.4 187.4 4227.0 44.3 36.8 862.6 42.6 369.2 9830.3 37.6
 Hypertensionc
  No 74.0 3210.6 23.0 481.0 14,210.5 33.8 795.0 18,481.4 43.0 140.0 3766.8 37.2 1490.0 39,669.2 37.6
  Yes 55.0 1230.6 44.7 298.0 5321.6 56.0 415.0 7545.2 55.0 116.0 1837.7 63.1 884.0 15,935.1 55.5
 Dyslipidemiad
  No 86.8 3243.2 26.7 531.2 13,480.2 39.4 760.4 16,156.2 47.1 132.9 3144.1 42.3 1511.2 36,023.8 41.9
  Yes 42.3 1198.0 35.3 247.8 6051.9 41.0 449.6 9870.4 45.6 123.2 2460.4 50.1 862.9 19,580.6 44.1
 Residential area
  East 20.5 851.1 24.0 151.1 3649.0 41.4 245.5 5122.4 47.9 59.6 1178.3 50.5 476.6 10,800.8 44.1
  Tatsukawa 13.3 697.6 19.1 116.7 3022.2 38.6 183.0 4637.6 39.4 38.4 959.9 40.0 351.4 9317.3 37.7
  South 22.5 620.7 36.3 97.9 2879.8 34.0 186.4 4059.6 45.9 46.4 888.7 52.2 353.2 8448.8 41.8
  Fudeoka 16.3 647.2 25.1 94.3 2459.2 38.4 141.4 3020.4 46.8 28.6 713.3 40.0 280.5 6840.1 41.0
  Center 25.1 557.9 45.0 109.0 2244.4 48.6 126.7 2538.5 49.9 25.4 443.3 57.2 286.2 5784.1 49.5
  Yoshiwara 11.2 387.4 28.9 90.2 2035.1 44.3 119.8 2397.9 50.0 20.3 498.5 40.7 241.4 5318.9 45.4
  West 11.1 384.4 28.9 70.1 1781.2 39.3 119.8 2344.9 51.1 22.3 548.6 40.7 223.3 5059.1 44.1
  Yogita 9.1 294.9 30.7 49.8 1461.2 34.0 87.6 1905.3 46.0 15.2 373.9 40.5 161.5 4035.3 40.0

Results for multiple imputed variables (overweight or obese, self-reported drinking status, self-reported smoking status, hypertension, dyslipidemia, and residential area) are averaged over 40 imputations.

BMI, Body mass index; HbA1c, Glycated hemoglobin; IR, Incidence rate; PY, Person-years.

aIncidence rate is reported per 1000 person-years.

bOverweight or obese is defined as a BMI ≥ 25 kg/m2.

cHypertension is defined as systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg.

dDyslipidemia is defined as serum low density lipoprotein cholesterol ≥ 140 mg/dL and/or serum high density lipoprotein cholesterol < 40 mg/dL.