Skip to main content
. 2023 Jun 16;117(Suppl 2):S107–S117. doi: 10.1016/j.ajcnut.2022.10.022

Table 4.

Promising antenatal interventions to prevent LBW, PTB, or SGA.

Antenatal interventions currently not recommended by WHO Intervention category
Replacement of IFA supplementation for pregnant women with MMN supplementation1 Nutrition
Prophylactic application of uterine cervical stitch (cerclage) for women at increased risk of PTB Other
Professionally provided psychosocial support for women at risk of giving birth to a LBW or preterm infant Other
Antenatal interventions recommended by WHO, for another indication2 Intervention category
Provision of high-dose calcium supplements (>1 g / day) to pregnant women in areas with low dietary calcium3 Nutrition
Provision of low-dose aspirin during pregnancy to women at increased risk of preeclampsia4 Other
Psychosocial interventions to reduce smoking in pregnancy5 Other
1

WHO recommendation sentence: Antenatal multiple micronutrient supplements that include iron and folic acid are recommended in the context of rigorous research.

2

Includes interventions without an indication to LBW, PTB, SGA or stillbirth in the recommendation sentence, or recommendation on malaria control in pregnancy

3

WHO recommendation sentence: In populations with low dietary calcium intake, daily calcium supplementation (1.5–2.0 g oral elemental calcium) is recommended for pregnant women to reduce the risk of pre-eclampsia.

4

WHO recommendation sentence: Low-dose acetylsalicylic acid (aspirin, 75 mg per day) is recommended for the prevention of pre-eclampsia in women at moderate or high risk of developing the condition.

5

WHO recommendation sentence: Health-care providers should ask all pregnant women about their tobacco use (past and present) and exposure to second-hand smoke as early as possible in the pregnancy and at every antenatal care visit.