Table 5.
Identified antenatal interventions for implementation research.
| Antenatal interventions for implementation research: interventions currently not recommended by WHO1 | Intervention category |
|---|---|
| Replacement of IFA supplementation for pregnant women with MMN supplementation2 | Nutrition |
| Antenatal interventions for implementation research: interventions currently recommended by WHO3 | Intervention category |
|---|---|
| Provision of proteins and energy to pregnant women with undernutrition4 | Nutrition |
| Dietary education for pregnant women with undernutrition 5 | Nutrition |
| Provision of insecticide-treated bed nets during pregnancy6 | Infection |
| Screening and treatment of asymptomatic bacteriuria in pregnancy7 | Infection |
| Changing a two-dose IPTp (intermittent preventive malaria treatment in pregnancy) regimen to more frequent IPTp dosing8 | Infection |
| Antenatal interventions recommended by the WHO, for another indication2 | Intervention category |
|---|---|
| Provision of low-dose aspirin during pregnancy to women at increased risk of preeclampsia9 | Other |
Includes interventions that are either not recommend or are recommended in the context of research.
WHO recommendation sentence: Antenatal multiple micronutrient supplements that include iron and folic acid are recommended in the context of rigorous research.
Includes interventions with an indication to LBW, PTB, SGA or stillbirth in the recommendation sentence, or recommendation on malaria control in pregnancy.
WHO recommendation sentence: In undernourished populations, balanced energy and protein dietary supplementation is recommended or pregnant women to reduce the risk of stillbirths and small-for-gestational-age neonates.
WHO recommendation sentence: In undernourished populations, nutrition education on increasing daily energy and protein intake is recommended for pregnant women to reduce the risk of low-birth-weight neonates.
WHO recommendation footnote: Integrated from the WHO publication Guidelines for the treatment of malaria (2015), [20] which also states: “WHO recommends that, in areas of moderate-to-high malaria transmission of Africa, IPTp-SP be given to all pregnant women at each scheduled ANC visit, starting as early as possible in the second trimester, provided that the doses of SP are given at least 1 month apart. WHO recommends a package of interventions for preventing malaria during pregnancy, which includes promotion and use of insecticide-treated nets, as well as IPTp-SP”. To ensure that pregnant women in endemic areas start IPTp-SP as early as possible in the second trimester, policy-makers should ensure health system contact with women at 13 weeks of gestation.
WHO recommendation sentence: A seven-day antibiotic regimen is recommended for all pregnant women with asymptomatic bacteriuria to prevent persistent bacteriuria, preterm birth and low birth weight.
WHO recommendation sentence: In malaria-endemic areas in Africa, intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) is recommended for all pregnant women. Dosing should start in the second trimester, and doses should be given at least one month apart, with the objective of ensuring that at least three doses are received.
WHO recommendation sentence: Low-dose acetylsalicylic acid (aspirin, 75 mg per day) is recommended for the prevention of pre-eclampsia in women at moderate or high risk of developing the condition [51].