TABLE 3.

Relative copy numbers and cysteine and methionine content of the structural proteins in reovirus virions and core particles

Protein	Mol wt (kDa)	No. of copies of proteina		No. of copies of cysteine and methionine			Relative proportion of cysteine and methionineb
		Virus	Core	Moleculec	Viriond	Core	Virion	Core
λ1	137.4	120	120	55	6,600	6,600	1.0	1.0
λ2	144.0	60	60	43	2,580	2,580	0.4	0.4
λ3	142.4	12	12	65	780	780	0.1	0.1
μ1c	76.3	600		20	12,000		1.8
μ2	83.3	21e	14	39	819	546	0.1	0.1
ς1	51.4	36		9	324		0.1
ς2	47.1	120e	120	18	2,160	2,160	0.3	0.3
ς3	41.2	600		27	16,200		2.5

^aDryden et al. (28). 

^bThe relative proportion of cysteine and methionine in each structure is normalized to the total copy number of cysteine (C) and methionine (M) in the λ1 protein by the following formula: [(copies of C and M for the protein) × (copies of the protein)] ÷ [(copies of C and M in λ1) × (copies of λ1)]. 

^cFrom published sequence data as follows: λ1 (7), λ2 (84), λ3 (99), μ1 (49, 98), μ1c (69), μ2 (97), ς1 (8), ς2 (25, 100), and ς3 (37). 

^dThe total cysteine and methionine in the structure for each protein was calculated by using the following formula: (total C and M in the protein) × (copies of protein). 

^eThe copy numbers of μ2 are from reference 20.