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. 2023 Aug 23;13:13803. doi: 10.1038/s41598-023-40726-0

Table 1.

Demographics, procedural details, and postoperative outcome in patients who underwent surgery with circulatory arrest or did not.

Circulatory arrest (n = 14) Non-circulatory arrest (n = 24) p Effect size (d) 95% CI
Age, years 76.1 ± 8.6 73.2 ± 6.7 0.254 0.39 [− 0.27, 1.05]
Sex, male/female 7/7 15/9 0.510 0.22 [− 0.42, 0.85]
IQCODE 3.1 ± 0.1 3.2 ± 0.2 0.297 0.36 [− 0.30, 1.02]
Hypertension 11 (78.6%) 5 (20.8%) 0.002 1.15 [0.42, 1.89]
Diabetes 2 (14.3%) 2 (8.3%) 0.977 0.01 [− 0.63, 0.65]
Coronary artery disease 2 (14.3%) 0 (0%) 0.250 0.38 [− 0.27, 1.03]
COPD 1 (7.1%) 0 (0%) 0.782 0.09 [− 0.55, 0.73]
CVA 0 (0%) 0 (0%)
Surgery
 Total arch replacement 8 (57.1%)
 Partial arch replacement 6 (42.9%)
 Abdominal aorta replacement 21 (87.5%)
 Thoracoabdominal aorta replacement 3 (12.5%)
 Circulatory arrest time, min 52.0 [47.0–57.0]
 Aortic cross clamp time, min 113.0 [100.0–122.0]
 Cardiopulmonary bypass time, min 142.5 [134.0–163.0]
 Operation time, min 309.0 [282.0–327.0] 114.0 [90.5–183.5]  < 0.001 1.34 [0.62, 2.07]
Postoperative outcome
 Overall mortality 0 (0%) 1 (4.2%)
 In-hospital mortality 0 (0%) 0 (0%)
 Postoperative stroke 0 (0%) 0 (0%)
 Silent embolic stroke on MRI 11 (78.6%) 4 (16.7%) 0.001 1.26 [0.51, 2.01]
 Silent microhemorrhage on MRI 2 (14.3%) 3 (12.5%) 1.000 0.00 [− 0.64, 0.64]
 Hospital stay, day 17.0 [14.0–23.0] 12.0 [8.5–19.0] 0.071 0.61 [− 0.05, 1.27]
 ICU stay, day 2.0 [1.0–3.0] 1.0 [1.0–2.5] 0.011 0.91 [0.20, 1.60]

Values expressed as mean ± standard deviation or median [interquartile range] for continuous data and number (percent) for categorical data.

CI, confidence interval, COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; IQCODE, Informant Questionnaire on Cognitive Decline in the Elderly; rsfMRI, resting-state functional magnetic resonance imaging; ICU, intensive care unit.