TABLE 1.
Lycopene accumulation in tissues.
| Tissues | Genotype P value | WT (vehicle) | WT | (Lycopene μg/g; μg/ml) |
DKO | |
|---|---|---|---|---|---|---|
| Bco1-/- | Bco2-/- | |||||
| Kidney | 0.0001 | n.d. | .23±.033ab | .32±.034ac | .23±.014b | .46±.037c |
| Heart | 0.0001 | n.d. | .15±.023a | .38±.031bc | .32±.012b | .58±.047c |
| Duodenum | 0.0101 | n.d. | 5.2±.871ab | 4.5±1.41a | 2.9±.341a | 7.0±1.40b |
| Spleen | 0.0001 | n.d. | .89±.264a | .90±.078ab | 2.0±.268b | 1.8±.220b |
| Adipose | 0.0088 | n.d. | .37±.064ab | .66±.105a | .36±.048b | .82±.149a |
| Testes | 0.0001 | n.d. | 1.2±.223a | 2.1±.273a | 3.8±.150a | 12.0±.323b |
| Seminal v esicles | 0.3327 | n.d. | .14±.077 | .11±.013 | .14±.011 | .22±.061 |
| Adrenals | NA | n.d. | 3.6 | 8.9 | 3.8 | 10.7 |
| Prostate | NA | n.d. | .34 | .53 | .30 | .80 |
| Ovaries | NA | n.d. | 2.3 | 3.1 | .95 | 9.7 |
One-way ANOVA was used to analyze for statistical significance. N = 9-12 per group (N = 4-7 for testes and seminal vesicles). Adrenals were pooled (n = 2), as well as prostate and ovaries (n = 1). Tissues not sharing the same letter in a row are significantly different (P < 0.05). NA = not applicable. n.d.= not detected.