TABLE 3.

Characteristics of genome regions studied^a

Genome region	Lytic transcription	Transcribed in latent peritoneal cells	Transcribed in latent spleen cells	Latency candidate	Comment(s) and references
K3	ND	No	No	No	BHV IE gene and KSHV K3 and K5 homolog (59, 76)
Gene 50	IEb	No	No	No	EBV R transactivator homolog (27, 76)
M8	E	No	No	No	Region transcribed with early kinetics (40)
ssDNABP gene	E	No	No	No	DNA replication (76)
DNApol gene	E	No	No	No	DNA replication (76)
M7	ND	No	No	No	Envelope glycoprotein gene (67)
gB gene	L (Fig. 3)	No	No	No	Glycoprotein gene (68)
MCP gene	L (Fig. 3)	No	No	No	Capsid gene (76)
M1	Yesc	No	No	No	Poxvirus serpin gene homolog, M3 homolog (6, 64, 76)
M2	Low (Fig. 3)	Yes	Yes	Yes	No known homologs
M3	Yes (Fig. 3)	No	Yes	Yes	No known homologs, secreted protein (75a), M1 homolog (6)
M4	ND	No	No	No	No known homologs
M5	ND	No	No	No	No known homologs
M6	ND	No	No	No	No known homologs
M9	Yes (Fig. 3)	No	Yes	Yes	No known homologs
M11	Low (Fig. 3)	Yes	No	Yes	v-bcl-2 gene (EBV, KSHV, HVS) (76)
Gene 72	Yesd	No	No	No	v-Cyclin gene (HVS, KSHV) (76)
Gene 73	Low (Fig. 3)	Yes	No	Yes	KSHV LANA gene homolog (32, 55, 76)
Gene 74	Low (Fig. 3)	Yes	No	Yes	Interleukin-8 receptor gene homolog (KSHV, HVS) (76)

^aAbbreviations: ND, not done; IE, immediate-early; E, early; L, late; BHV, bovine herpesvirus 4. 

^bReference 39a. 

^cReference 12a. 

^dData not shown and reference 75b.