Table 2.
Tumor and treatment details in the two groups of patients
| Control (N = 65) | Triphala (N = 37) | Chi square/unpaired t test | ||
|---|---|---|---|---|
| Tumor Size (T) | T1 | 2 (3.08) | 1 (2.7) | |
| T2 | 29 (44.62) | 14 (37.84) | ||
| T3 | 19 (29.23) | 11 (29.73) | ||
| T4 | 12 (18.46) | 9 (24.32) | ||
| TX | 3 (4.62) | 1 (2.7) | ||
| Nodes | N0 | 22 (33.85) | 13 (35.14) | |
| N1 | 25 (38.46) | 15 (40.54) | ||
| N2 | 15 (23.08) | 7 (18.92) | ||
| N3 | 2 (3.08) | 1 (2.7) | ||
| NX | 1 (1.54) | 1 (2.7) | ||
| Metastasis | M0 | 53 (81.54) | 29 (78.38) | |
| MX | 12 (18.46) | 8 (21.62) | ||
| Surgery before radiation | Yes | 23 (35.38) | 16 (43.24) | |
| No | 42 (64.62) | 21 (56.76) | ||
|
Radiation type and dose |
Radiation only | 28 (43.08) | 12 (32.43) | |
| Chemo-radiation | 37 (56.92) | 25 (67.57) | ||
| Radiation fraction | 33.43 ± 2.03 | 33.65 ± 1.75 | ||
| Radiation dose | 66.9 ± 4.05 | 67.30 ± 3.50 | ||
| Early incidence of treatment breaks (before week 4) | No treatment breaks | 59 (90.77) | 36 (97.3) | |
| Treatment breaks | 6 (9.23) | 1 (2.70) | ||
| Late incidence of treatment breaks (after week 4) | No treatment breaks | 52 (80.00) | 36 (97.29) | |
| Treatment breaks | 13 (20.00) | 3 (8.11) | ||
| Total incidence of treatment breaks | No treatment breaks | 46 (70.77) | 33 (89.19) | Chi square P = 0.032 |
| Treatment breaks | 19 (29.23) | 4 (10.81) | ||
| Treatment days lost | 6.78 ± 0.54 | 5.00 ± 3.43 | t test P = 0.02 | |
| Feeding tube | Yes | 18 (27.69) | 7 (18.92) | |
| No | 47 (72.31) | 30 (81.08) | ||
| Mucositis | Intolerable | 54 (83.08) | 27 (72.97) | |
| Tolerable | 11 (16.92) | 10 (27.03) | ||
| Opiod use | Yes | 49 (75.38) | 19 (51.35) | Chi square P = 0.013 |
| No | 16 (24.62) | 18 (48.65) | ||
| Weight loss | Initial weight | 53.40 ± 11.11 | 52.29 ± 14.87 | |
| Final weight | 49.72 ± 10.80 | 49.32 ± 14.39 | ||
| Weight change | 3.66 ± 1.70 | 2.97 ± 1.52 | t test P = 0.038 | |
| Less than 2 kg | 27 (41.54) | 21 (56.76) | ||
| 2.1 to 5 kg | 30 (46.15) | 14 (37.84) | ||
| More than 5 kg | 9 (13.85) | 2 (5.41) | ||
| Treatment response | Complete Response | 45 (69.23) | 28 (75.68) | |
| Partial response | 11 (16.92) | 4 (10.81) | ||
| No response | 9 (13.85) | 5 (13.51) |