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. 2023 Jun 8;11(3):327–341. doi: 10.1007/s40487-023-00233-8

Table 4.

Factors affecting disease-free survival (DFS) and overall survival (OS)

Factors No. of patients DFS OS
5-Year 10-Year p 5-Year 10-Year p
% % % %
Age, years 0.890 0.674
 < 50 83 38.6 29.8 55.0 37.6
 ≥ 50 43 37.1 29.7 48.8 34.9
Menopausal status 0.383 0.274
 Premenopausal 92 36.9 28.8 50.7 33.9
 Postmenopausal 34 41.2 32.4 58..8 44.1
Histological grade 0.293 0.669
 1 or 2 92 41.3 29.8 52.8 36.0
 3 13 23.1 23.1 46.2 30.8
Clinical tumor stage 0.047 0.017
 T1–T2 23 52.2 43.5 69.6 56.5
 T3–T4 103 34.9 26.6 49.1 32.2
Clinical nodal stage 0.041 0.036
 N0/N1/N2 107 42.0 34.2 55.1 40.0
 N3 19 15.8 5.3 39.1 8.4
Clinical stage 0.086 0.026
 IIIA 58 43.0 37.5 60.3 48.2
 IIIB 49 40.8 30.4 49.0 32.4
 IIIC 19 15.8 5.3 39.1 8.4
HER2 status 0.020 0.031
 Negative 52 47.9 37.7 67.3 45.8
 Positive 45 28.9 22.2 46.7 31.1
HR status 0.004 0.004
 Negative 51 23.5 19.6 37.3 25.5
 Positive 71 49.2 37.3 65.8 45.6
Pathological response 0.030 0.003
 pCR 32 53.1 43.8 75.0 59.4
 Non-pCR 94 32.9 25.0 45.2 28.9

HR hormone receptor, pCR pathological complete response, HER2 human epidermal growth factor receptor 2