Table 3.

Current recommendations for corticosteroid use in COVID-19

Guideline (reference)	EMA [11]	WHO [9]	IDSA [12]	ERS [10]	NIH [13]
Preferred drug	Dexamethasonea	Dexamethasoneb	Dexamethasonec	Dexamethasone	Dexamethasoned
Daily dose in mg	6	6	6	6	6
Duration in days	For a maximum of 10 days	For a maximum of 10 days	For 10 days or until hospital discharge	For a maximum of 10 days	For 10 days or until hospital discharge
Degree of recommendation		Strong	Conditional	Strong
Strength of evidence		Moderate	Moderate
Year	2020	2020	2022	2020	2020

^aRecommended orally or intravenously from 12 years of age and weighing at least 40 kg in subjects requiring supplemental oxygen therapy

^bRecommended in individuals with severe or critical COVID-19 disease, but not (conditional recommendation, low strength of evidence) in subjects with nonserious disease

^cRecommended in subjects with severe COVID-19 disease, but not in those without hypoxemia (conditional recommendation, low strength of evidence)

^dRecommended in subjects with severe COVID-19 disease, but not those without hypoxemia