Table 2.

Analysis of combined rT7SS (AM + PM)—ITT population

Variable time point	Treatment	N	Mean (SD)	LSM	Source	p value	Treatment difference [95% (CI)]
Baseline	MP-AzeFlu	300	25.40 (6.96)	25.08	Treatment	0.6703
	Aze	298	24.89 (7.07)	24.61
	Flu	299	24.97 (7.33)	24.72
Day 2 to day 7 change from baseline (AM + PM)	MP-AzeFlu	300	− 8.33 (7.64)	− 8.11
	Aze	298	− 5.20 (7.58)	− 5.95	MP-AzeFlu vs. Aze	< 0.0001	− 1.73 (− 3.05, − 1.28)
	Flu	299	− 6.55(8.01)	− 6.24	MP-AzeFlu vs. Flu	< 0.0001	− 1.17 (− 2.76, − 0.99)
Day 2 to day 14 change from baseline (AM + PM)	MP-AzeFlu	300	− 11.00 (8.71)	− 10.69
	Aze	298	− 7.17 (8.87)	-8.29	MP-AzeFlu vs. Aze	< 0.0001	− 1.96 (− 3.26, − 1.54)
	Flu	299	− 9.77 (9.31)	− 9.10	MP-AzeFlu vs. Flu	0.0003	− 0.98 (− 2.44, − 0.73)