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. 2023 Mar 3;75(3):1502–1510. doi: 10.1007/s12070-023-03599-3

Table 1.

Biochemical hypocalcaemia and its association with various parameters

Parameters Yes
(n = 51)
p value
Age (Years) 47.27 ± 13.69 0.2621
Age 0.8992
21–30 Years 4 (7.8%)
31–40 Years 15 (29.4%)
41–50 Years 13 (25.5%)
51–60 Years 7 (13.7%)
61–70 Years 9 (17.6%)
71–80 Years 3 (5.9%)
Gender 0.7132
Male 7 (13.7%)
Female 44 (86.3%)
Neck Swelling (Yes) 48 (94.1%) 0.5622
Pressure Symptoms 0.7112
No 48 (94.1%)
Horseness Of Voice 1 (2.0%)
Dysphagia With Stridor 1 (2.0%)
Shortness Of Breath 1 (2.0%)
TFT 1.0002
Normal 50 (98.0%)
Hypothyroidism 1 (2.0%)
USG Neck 0.8872
Tirads 1 5 (9.8%)
Tirads 2 21 (41.2%)
Tirads 3 1 (2.0%)
Tirads 4 17 (33.3%)
Tirads 5 5 (9.8%)
Thyroiditis 1 (2.0%)
Solitary Thyroid Nodule 1 (2.0%)
FNAC: Colloid Goiter (Yes) 21 (41.2%) 0.0923
FNAC: Adenomatoid Nodule (Yes) 4 (7.8%) 1.0002
FNAC: Papillary Carcinoma (Yes) 8 (15.7%) 0.1862
FNAC: Nodular Goiter (Yes) 2 (3.9%) 1.0002
FNAC: Follicular Neoplasm (Yes) 8 (15.7%) 0.4772
FNAC: Thyroiditis (Yes) 3 (5.9%) 0.5682
FNAC: Others (Yes) 6 (11.8%) 0.6702
Procedure 1.0002
Near Total Thyroidectomy 5 (9.8%)
Total Thyroidectomy 46 (90.2%)
Parathyroid (Preserved) 51 (100.0%) 1.0003
Inferior Thyroid Artery (Preserved) 51 (100.0%) 1.0003
Vitamin D (ng/mL) (Pre-Operative) 19.18 ± 9.09 0.2164
Vitamin D (Pre-Operative) 0.3852
<20 ng/mL 33 (64.7%)
20–30 ng/mL 14 (27.5%)
≥30 ng/mL 4 (7.8%)
PTH (pg/mL) (Pre-Operative) 48.05 ± 20.03 0.8484
PTH (pg/mL) (Post-Operative 4 h)*** 19.00 ± 16.02 0.0014
PTH (Pre-Operative) 0.7152
15–65 pg/mL 42 (82.4%)
>65 pg/mL 9 (17.6%)
PTH (Post-Operative 4 h)*** < 0.0013
<15 pg/mL 28 (54.9%)
15–65 pg/mL 23 (45.1%)
Calcium (mg/dL) (Pre-Operative) 9.04 ± 0.44 0.2304
Calcium (mg/dL) (POD 1)*** 8.16 ± 0.57 < 0.0011
Calcium (mg/dL) (POD 2–4)*** 7.78 ± 0.60 < 0.0014
Calcium (mg/dL) (3 Months) 8.99 ± 0.87 0.0614
Biochemical Hypocalcemia (Pre-Operative) (Yes) 8 (15.7%) 0.1012
Biochemical Hypocalcemia (POD 1) (Yes)*** 42 (60.0%) < 0.0013
Biochemical Hypocalcemia (POD 2–4) (Yes)*** 51 (73.9%) < 0.0013
Biochemical Hypocalcemia (3 Months) (Yes) 10 (22.7%) 0.0982
Symptomatic Hypocalcemia (Yes)*** 25 (49.0%) 0.0013
Post Operative Complications 1.0002
No 49 (96.1%)
Horseness Of Voice 2 (3.9%)
Post Operative Management: No (Yes) 9 (17.6%) 0.1022
Post Operative Management: IV Calcium (Yes)*** 18 (35.3%) 0.0152
Post Operative Management: Oral Calcium (Yes) 41 (80.4%) 0.1212
Post Operative Management: Vitamin D (Yes) 14 (27.5%) 0.5282
Discharged with Calcium Supplementation: No (Yes) 9 (18.4%) 0.2052
Discharged with oral Calcium and vitamin DSupplementation 40 (81.6%) 0.2052
Final HPE Impression 1.0003
Benign 34 (66.7%)
Malignant 17 (33.3%)
Change in PTH (pg/mL) (Post-Operative 4 h)*** -29.05 ± 22.81 0.0324