Table 3.

Binding energy and interactions of active compounds with TNF protein.

Protein-ligand complex	Binding Affinity (kcal/mol)	RMSD	Interacting residues
TNF_Licoflavanone	−12.4931	1.738838	GLY B: 24, LYS B: 65, ASP B: 140
TNF_Skrofulein	−11.2147	1.383699	GLY B: 24, GLU B: 23, ASP B: 140
TNF_(+)-Catechin	−10.2839	2.247661	GLY B: 24, LYS B: 65
TNF_Stigmasterone	−9.45824	2.158878	GLY B: 24, ASP B: 143
TNF_5,7-Dihydroxy-4′-methoxy-8,3′-di-C-prenylflavanone	−9.4248	1.283021	LEU B:26, ALA B: 22