Compounds	BChE IC50 (μM)	BChE-ligands interactions
4h	−9.52	O72	OD1-ASP283	HBD	2.38
		O72	OD2-ASP283	HBD	2.30
		C42	6-Ring-TYR332	H–π	2.70
		6-Ring	5-Ring-TRP82	π–π	2.61
SM3	−7.15	N41	O-SER287	HBD	2.14
		O30	N-GLY115	HBA	2.39
4i	−6.98	S11	OG-SER198	HBA	2.12
		C8	5-Ring-TRP82	H–π	2.81
Galantamine	−6.66	O18	OE2-GLU197	HBD	2.76
		O18	N-GLY116	HBA	2.04
4k	−4.12	S11	OG-SER198	HBA	2.51
		6-Ring	CE1-PHE329	H–π	2.94
4q	−3.36	S11	OG-SER198	HBA	2.52
		6-Ring	CB-ASN68	H–π	2.56