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. 2023 Aug 11;41:20–32. doi: 10.1016/j.jot.2023.06.003

Figure 1.

Figure 1

Bioinformatics prediction of the molecular mechanisms involving SMSC-Exo in the occurrence and development of OA. A, Venn diagram showing the intersection genes between 3 ​d after sham and DMM operations and 7 ​d after sham and DMM operations. B, heatmap showing the expression of the 22 intersection genes 3 ​d after the sham and DMM operations (sham 3 ​d n ​= ​3, DMM 3 ​d n ​= ​3). C, heatmap showing the expression of the 22 intersection genes 7 ​d after the sham and DMM operations (sham 7 ​d n ​= ​3, DMM 7 ​d n ​= ​3). D-E, Expression of MATN3 in GSE26475 at 3 ​d and 7 ​d after DMM operation. F, PPI analysis of MATN3 in the Genemania database yielded 22 interacting proteins. G, KEGG enrichment analysis of 22 interacting proteins (bubble color indicates p-value, The darker the color, the smaller the p-value; Size indicates the number of genes). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)