FIGURE 2.

Sketch of the differentiation progression of the cells involved in neurulation. Starting from Ectoderm Stem cells, neural ectoderm and epithelial stem cells emerge. Neural ectoderm stem cells further differentiate in the progenitors of neural and neural crest cells. While neural crest cells will in turn differentiate into several different mature cells, neural progenitors end up producing astrocytes, oligodendrocytes, and neurons. As differentiation proceeds, cells progressively lose differentiation potential and renewal ability.