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Factors that affect bone graft incorporation.
| Factors | Promotes | Impairs |
|---|---|---|
| 1. Local | Vascularity | Infection |
| Mechanical Stability | Radiation | |
| Growth factors | Tumour | |
| Innervation | ||
| 2. Systemic | Growth hormones | Steroids |
| Parathyroid hormones | Non-steroidal anti-inflammatory drugs | |
| Insulin-like growth factors | Smoking | |
| Somatomedins | Malnutrition | |
| Thyroid hormones | Diabetes | |
| Vitamins A & D | Chemotherapy | |
| Metabolic bone disease |
