Table 2. Analgesic Activity (Acetic Acid-Induced Writhing) of Indomethacin Derivatives.

treated group	dose (mg/kg i.p.)	no. of writhing (20 min)	percent Analgesia (%)
normal saline	10	37.50 ± 1.25
indomethacin	10	17.04 ± 1.22***	51.23
test compound 2a	10	14.33 ± 1.43***	61.79
	20	12.17 ± 0.70***	67.55
	30	5.17 ± 1.33***	86.22
test compound 2b	10	14.67 ± 1.89***	60.88
	20	11.50 ± 0.76***	69.33
	30	10.00 ± 1.00***	73.33
test compound 2c	10	16.50 ± 1.65***	56.00
	20	12.50 ± 1.67***	66.33
	30	10.00 ± 1.79***	73.33
test compound 2e	10	15.17 ± 1.54***	59.55
	20	10.83 ± 1.68***	71.12
	30	9.33 ± 1.33***	75.12
test compound 2f	10	15.50 ± 1.06***	58.67
	20	13.33 ± 1.58***	64.46
	30	7.50 ± 2.04***	80.00
test compound 2g	10	20.17 ± 1.49***	46.21
	20	13.67 ± 1.67***	63.55
	30	6.33 ± 1.78***	83.11