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. Author manuscript; available in PMC: 2023 Aug 24.
Published in final edited form as: Ostomy Wound Manage. 2018 Jun;64(6):30–40.

Table 2.

Reported ileostomy neoplasia following total proctocolectomy for familal adenomatous polyposis

Author, year
(reference number)
Age at
FAP
diagnosis
Interval from
surgery to
ICa (years)
Age
at Ica
(years)
Histology Lesion pathology
Roth, 1982 (54) 35 9 44 ACa Adenomatous polyps
Ross, 1987 (55) 24 32 56 ACa Adenocarcinoma
Suarez, 1988 (15) 11 29 40 ACa Adenomatous changes with mild dysplasia
Primrose, 1988 (56) 47 25 72 ACa Adenomatous changes with mild dysplasia
Lopez, 1991(57) 23 27 50 ACa Adenomatous polyps
Gilson, 1992 (58) 29 40 69 ACa Adenomatous polyps
Lux, 1993 (59) 47 25 72 ACa Adenomatous polyps
Johnson, 1993 (23) 40 25 65 ACa Colonic metaplasia
Wu, 1998 (60) 25 42 67 ACa and SCC Adenomatous polyposis gene
Mumira, 1999 (61) 33 21 54 ACa Well-differentiated adenocarcinoma with submucosainvasion
Iizuki, 2002 (62) 55 14 69 ACa Not reported
Hata, 2003 (63) 25 32 57 ACa Adenomatous polyps
Shenoy, 2009 (64) 25 10 60 ACa Tubulovilous adenocarcinoma
Huntington, 2017 (65) 17 24 41 ACa Tubulovilous adenocarcinoma
Procaccino, 2015 (53) 48 30 78 ACa Moderate differentiated adenocarcinoma

TPC=total proctocolectomy; FAP=familial adenomatous poplyposis; ACa=adenocarcinoma; ICa=ileostomy cancer