Table 2.
Author, year (reference number) |
Age at FAP diagnosis |
Interval from surgery to ICa (years) |
Age at Ica (years) |
Histology | Lesion pathology |
---|---|---|---|---|---|
Roth, 1982 (54) | 35 | 9 | 44 | ACa | Adenomatous polyps |
Ross, 1987 (55) | 24 | 32 | 56 | ACa | Adenocarcinoma |
Suarez, 1988 (15) | 11 | 29 | 40 | ACa | Adenomatous changes with mild dysplasia |
Primrose, 1988 (56) | 47 | 25 | 72 | ACa | Adenomatous changes with mild dysplasia |
Lopez, 1991(57) | 23 | 27 | 50 | ACa | Adenomatous polyps |
Gilson, 1992 (58) | 29 | 40 | 69 | ACa | Adenomatous polyps |
Lux, 1993 (59) | 47 | 25 | 72 | ACa | Adenomatous polyps |
Johnson, 1993 (23) | 40 | 25 | 65 | ACa | Colonic metaplasia |
Wu, 1998 (60) | 25 | 42 | 67 | ACa and SCC | Adenomatous polyposis gene |
Mumira, 1999 (61) | 33 | 21 | 54 | ACa | Well-differentiated adenocarcinoma with submucosainvasion |
Iizuki, 2002 (62) | 55 | 14 | 69 | ACa | Not reported |
Hata, 2003 (63) | 25 | 32 | 57 | ACa | Adenomatous polyps |
Shenoy, 2009 (64) | 25 | 10 | 60 | ACa | Tubulovilous adenocarcinoma |
Huntington, 2017 (65) | 17 | 24 | 41 | ACa | Tubulovilous adenocarcinoma |
Procaccino, 2015 (53) | 48 | 30 | 78 | ACa | Moderate differentiated adenocarcinoma |
TPC=total proctocolectomy; FAP=familial adenomatous poplyposis; ACa=adenocarcinoma; ICa=ileostomy cancer