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. 2023 Aug 10;14:1174140. doi: 10.3389/fimmu.2023.1174140

Figure 6.

Figure 6

Prevention and reversion of radiation-induced endotoxemia and systemic inflammation by HD5. (A-D) Adult mice were fed a liquid diet with vehicle (Veh-Sham & Veh-IR) or HD5 (HD5-Sham & HD5-IR) for 24 hours before sham treatment (Sham) or irradiated (IR). At 24 hours after irradiation, plasma LPS (A), TNFα (B), IL-6 (C), and IL-1β (D) were measured. Values are mean ± sem (n = 6); *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001 for significant difference between the indicated groups; “ns” = not significant. (E-H) At 24 hours after sham treatment (Sham) or irradiation (IR), mice were fed a liquid diet with vehicle (Sham-Veh & IR-Veh) or HD5 (Sham-HD5 & IR-HD5). After additional 24 hours, plasma LPS (E), TNFα (F), IL-6 (G), and IL-1β (H) were measured. Values are mean ± sem (n = 6); *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001 for significant difference between the indicated groups; “ns”, not significant.