Table 2.
Oxytocin | Placebo | Difference/test | ||||
---|---|---|---|---|---|---|
Mean (s.d.) | Median (IQR) | Mean (s.d.) | Median (IQR) | Rank biserial correlation (P) | Z statistic | |
Primary outcome measures (n) | ||||||
Gaze toward the eye region, % of time (68) | 29.9 (18.0) | 25.3 (28.4) | 31.5 (19.9) | 29.9 (30.9) | 0.07 (0.60) | −0.53 |
Trust in the physician, WFPTS, range=1–5 (68) | 3.8 (0.6) | 3.7 (0.9) | 3.8 (0.7) | 3.8 (1) | −0.01 (0.86) | −0.08 |
Secondary outcome measures (n) | ||||||
Satisfaction with physician, range = 0–100 (64) | 60.5 (23.1) | 67.0 (26) | 61.9 (22.4) | 67 (26.8) | 0.18 (0.23) | −1.19 |
Physicians' communication style – affiliativeness, range = 0–60 (68) | 42.8 (6.6) | 44.0 (7) | 42.3 (6.2) | 43.5 (7) | −0.14 (.34) | −0.96 |
Physician’s communication style – dominance/activity, range = 0–25 (68) | 9.3 (2.9) | 9.0 (4) | 9.7 (2.7) | 9.0 (3) | 0.18 (0.25) | −1.16 |
Free recall of information, range = 0–5 (68) | 3.7 (1.0) | 4.0 (1.5) | 3.4 (1.1) | 3.5 (1.5) | −0.25 (0.09) | −1.69 |
Recognition of information, range = 0–5 (68) | 4.0 (0.9) | 4.0 (1) | 3.7 (0.9) | 4.0 (1) | −0.21 (0.19) | −1.30 |
Pupil diameter, in millimeters (60) | 4.3 (0.5) | 4.3 (0.6) | 4.3 (0.5) | 4.2 (0.7) | −0.06 (0.70) | −0.39 |
Exploratory measures (n) | ||||||
Change in positive affect, PANAS (67) | −1.3 (4.3) | −1.0 (4.5) | −1.4 (4.6) | −1.0 (5.3) | 0.00 (1.00) | 0.00 |
Change in negative affect, PANAS (67) | −0.8 (2.6) | −1.0 (2) | −1.0 (2.6) | −1.0 (3) | −0.13 (0.38) | −0.89 |
Change in state anxiety (STAI-S) (67) | −0.6 (2.2) | 0.0 (3) | −0.5 (2.3) | 0.0 (2.3) | −0.02 (0.91) | −0.12 |
IQR, interquartile range; PANAS, Positive And Negative Affect Scale; s.d., standard deviation; STAI-S, State-Trait Anxiety Inventory – State; WFPTS, Wake Forest Physician Trust Scale.