. 2023 Aug 2;12(9):e230013. doi: 10.1530/EC-23-0013
This work is licensed under a Table 2.
Correlations between increases in 25(OH)D levels and biomarkers among TG responders and TG nonresponders: mean ± s.d.for normally distributed variables or median (interquartile range) for non-normally distributed variables.
| Serum TG response to 25(OH)D | TG responders (n = 55) | TG nonresponders (n = 63) | P-value |
|---|---|---|---|
| Age (years) | 54.4 ± 10.0 | 54.3 ± 11.2 | 0.97 |
| Female, n (%) | 32 (58) | 33 (52) | 0.52 |
| BMI (kg/m2) | 24.8 (21.7–28.4) | 23.7 (21.2–27.2) | 0.22 |
| Use of lipid-lowering medication, n (%) | 16 (29) | 20 (31) | 0.75 |
| History of DM, n (%) | 6 (10) | 10 (15) | 0.43 |
| History of hypertension, n (%) | 14 (25) | 11 (17) | 0.28 |
| History of cancer, n (%) | 4 (7) | 2 (3) | 0.55 |
| Baseline 25(OH)D (ng/mL) | 20.6 (15.4–27.3) | 26 (20.6–31.2) | <0.01 |
| Baseline TGs (mg/dL) | 141 (90–210) | 98 (74–133) | <0.01 |
| Baseline TC (mg/dL) | 192.4 ± 36.0 | 184.2 ± 40.6 | 0.25 |
| Baseline LDL-C (mg/dL) | 118.1 ± 29.9 | 112.8 ± 29.3 | 0.37 |
| Baseline HDL-C (mg/dL) | 47 (42–60) | 52 (43–60) | 0.30 |
| Baseline HbA1c (%) | 5.7 (5.5–6.1) | 5.6 (5.4–6.2) | 0.93 |
| Baseline BUN (mg/dL) | 11 (9.5–14) | 11 (8.8–14) | 0.62 |
| Baseline creatinine (mg/dL) | 0.8 (0.6–0.9) | 0.7 (0.6–0.9) | 0.78 |
| Baseline albumin (g/dL) | 4.4 ± 0.2 | 4.4 ± 0.2 | 0.84 |
| Baseline AST (U/L) | 19 (17–21) | 19 (18–23) | 0.88 |
| Baseline ALT (U/L) | 20 (13–33) | 18 (14–25) | 0.48 |
| Baseline total bilirubin (mg/dL) | 0.8 (0.5–0.9) | 0.9 (0.6–1.4) | 0.06 |
| Baseline Alk-p (U/L) | 60 (46–64) | 58 (46–67) | 0.88 |
| Baseline γ-GT (U/L) | 21 (14–38) | 22 (15–31) | 0.76 |
| Baseline uric acid (mg/dL) | 5.5 (4.8–6.5) | 5.5 (4.7–6.2) | 0.67 |
| Baseline Hb (g/dL) | 14.4 ± 1.4 | 14.6 ± 1.1 | 0.53 |
| Baseline Hct (%) | 42.3 ± 3.6 | 43.1 ± 2.9 | 0.29 |
| Baseline MCH (pg) | 31.4 (30–32) | 31.0 (30–32) | 0.86 |
| Baseline MCV (fL) | 90 (86–93) | 90 (88–92) | 0.63 |
| Baseline WBC (103/µL) | 6.5 (5.4–7.9) | 6.0 (5.1–7.3) | 0.17 |
| Baseline platelets (103/µL) | 237 (199–257) | 217 (184–263) | 0.49 |
25(OH)D, 25-hydroxyvitamin D; AST, aspartate transaminase; ALT, alanine transaminase; Alk-p, alkaline phosphatase; BUN, blood urea nitrogen; γ-GT, γ-glutamyl transpeptidase; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; Hb, hemoglobin; Hct, hematocrit; LDL-C, low-density lipoprotein cholesterol; MCH, mean corpuscular hemoglobin; MCV, mean corpuscular volume; TGs, triglycerides; TC, total cholesterol; WBC, white blood cell count.