TABLE 2.

Asialo GM1⁺ cells in vehicle- and IL-18-administered BALB/c mice treated with NRS or anti-asialo GM1 antibody 26 h after i.p. inoculation with 10⁴ PFU of HSV-1

In vivo treatment	Mean % asialo GM1+a
	Peritoneal cells	Splenocytes
NRSb + vehiclec	5.1	14.4
AGMd + vehicle	−0.3	1.6
NRS + IL-18	17.4	9.7
AGM + IL-18	2.3	−3.0

^aA cytotoxicity test using NRS or anti-asialo GM1 antibody plus complement was conducted to determine the percentage of asialo GM1⁺ cells. 

^bNRS or anti-asialo GM1 antibody was injected i.p. on days 3 and 1 before infection. 

^cOn days 2 and 1 before infection and days 0 and 1 of infection, 1 μg of IL-18 was injected i.p. into each mouse (n = 2 per group), and the mice were sacrificed to prepare peritoneal cells and splenocytes 2 h after a final injection with the vehicle or IL-18. 

^dAGM, anti-asialo GM1 antibody.