Table 3.

Association between DM and longitudinal risk of KOA worsening, PS-matched KOA patients with versus without DM

Outcomes	Hazard ratio (95%CI), p
KOA JSN progression	0.87 (0.55–1.37), p: 0.536
Knee replacement surgery	1.01 (0.56–1.8), p: 0.983
NASS incidence	1.70 (1.18–2.46), p: 0.005 *

Cox proportional hazards analysis was used. Independent variable: DM versus no DM (reference); DM was associated with an increased risk of NASS incidence over the follow-up of up to 9 years. CI confidence interval, DM diabetes mellitus, JSN joint space narrowing, KOA knee osteoarthritis, NASS non-acceptable symptomatic state, PS propensity score

^*Significant FDR-corrected p values