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. 2023 Aug 23;15(2):2246185. doi: 10.1080/19490976.2023.2246185

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© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 3. — Heatmap showing the longitudinal association between 1-year change CQI-related genera and 1-year change in cardiovascular risk factors. Association tested with linear mixed model and adjusted for intervention group, timepoint, recruiting center (Alicante, Barcelona, Reus, Valencia), smoking status (former smoker, never smoked, smoker), diabetes status, sex, age categories (below the median, < 65 years old; above the median, > 65 years old). Participant ID was set as random effect. For each cell, colors indicate the association coefficient with cardiovascular risk factors and asterisks denote significance. *p < 0.05; **p < 0.01. TG, triglycerides FPG, fasting plasma glucose; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HOMA, homeostasis model assessment; HbA1c, glycated hemoglobin.