Table 1.

Hyperparameters of the mean and variance batch effects used in the simulation studies. The “Data” column refers to the parameter values estimated based on the original data. The “Small” and “Large” columns refer to the parameter values used for simulating data with small and large batch effects, respectively

Batch
	Data	Small	Large	Data	Small	Large	Data	Small	Large	Data	Small	Large
1	–0.04	–0.04	–0.4	0.15	0.15	0.15	60	60	100	60	60	100
2	0.15	0.15	1.5	0.35	0.35	0.35	100	100	120	100	100	40
3	–0.15	–0.15	–1.5	0.82	0.82	0.82	56	56	100	50	50	60
4	–0.1	–0.1	1.0	0.46	0.46	0.46	30	30	60	30	30	100
5	–0.08	–0.08	–0.8	0.12	0.12	0.12	100	100	40	100	100	120