Table 3.

Clinical Course of Infectious Keratitis Stratified by Drug Use Status

	Opioid Users (n = 24)	Non-Opioid Drug Users (n = 74)	Non-Drug Users (n = 50)
Initial Ulcer Location
Central	9 (37.5%)	28 (37.8%)	16 (32.0%)
Peripheral	7 (29.2%)	22 (29.7%)	14 (28.0%)
Unknown	8 (33.3%)	24 (32.4%)	20 (40.0%)
Hospitalized
Yes	15 (62.5%)***	24 (32.4%)	6 (12.0%)**
No	7 (29.2%)***	40 (54.1%)	39 (78.0%)**
Unknown	2 (8.3%)	10 (13.5%)	5 (10.0%)
Lost to Follow-Up
Yes	15 (62.5%)	37 (50.0%)	12 (24.0%)*
No	7 (29.2%)	28 (37.8%)	30 (60.0%)*
Unknown	2 (8.3%)	9 (12.2%)	8 (16.0%)
Compliant with Medications
Yes	9 (37.5%)	36 (48.6%)	24 (48.0%)
No	9 (37.5%)	18 (24.3%)	15 (30.0%)
Unknown	6 (25.0%)	20 (27.0%)	11 (22.0%)
Bilateral Ulcers	3 (12.5%)	3 (4.1%)	1 (2.0%)
Positive Culture Growth	17 (70.8%)	51 (68.9%)	26 (52.0%)
Polymicrobial Infection	11 (45.8%)	22 (29.7%)	14 (28.0%)
Subconjunctival Antibiotics Used	3 (12.5%)	10 (13.5%)	6 (12.0%)
Fortified Topical Antibiotics Used	19 (79.2%)**	44 (59.5%)	19 (8.0%)*
Emergent Penetrating Keratoplasty or Glue	2 (8.3%)	6 (8.1%)	2 (4.0%)

^*Chi-square p-value < 0.05

^**Chi-square p-value < 0.01

^***Chi-square p-value < 0.001