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. Author manuscript; available in PMC: 2024 Aug 22.
Published in final edited form as: Circulation. 2023 Aug 21;148(8):679–694. doi: 10.1161/CIRCULATIONAHA.123.062847

Table 4.

Description of Assays Utilized to Evaluate Immunosuppression

Technology Description Commercially Available Assay Research Assay
T Cell Assay Bioluminescent quantification of intracellular ATP from activated CD4 T lymphocytes Immuknow®
Interferon Quantification Solid-phase, enzyme-linked immunosorbent assay for spectrophotometric estimation of secreted antibody ImmunoSpot®
GEP of mRNA Gene expression profiling of peripheral blood mononuclear cells AlloMap®
Torque teno virus PCR assay for detection and quantitation of circulating torque teno virus Biomerieux TTV R-GENE®

ATP, adenosine triphosphate; GEP, gene expression profiling; mRNA, messengerRNA; TTV, Torque Teno Virus