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Geometric mean (with 95% confidence interval) ocular IgA responses on study day 42 of animals immunized with S. flexneri 2a (A), S. flexneri 3a (B), S. flexneri 6 (C), and S. sonnei (D) InvaplexAR formulations and the species LPS (I), IpaB (II), and IpaC (III). Stars represent significance compared to saline-treated animals (*P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001). P-values were determined by Kruskal-Wallis test with Dunn’s post hoc correction.
