TABLE 3.
Viral defense and regulatory proteins found in each prophage
| Viral defense proteins | Regulatory proteins | |||||||
|---|---|---|---|---|---|---|---|---|
| Prophage | Acr a | Glycosyltransferases and acetylases | Defense against restriction/modification systems | TA systems | DNA scission proteins | QS | Latency promoting repressors | Other proteins |
| vB_PaeM-D14A | 1 (7) | ND b | DNA-cytosine methyltransferase | ND | ND | TraR homolog | CII Cro/cI |
ND |
| vB_PaeS-D14B | 1 (6) | ND | ND | Putative toxin, BrnT family Putative antitoxin, CopG family |
ND | LuxR family protein | Cro CI |
ND |
| vB_PaeS-D14C | 1 (2) | Glycosyltransferase family 9 | S-adenosyl-L-methionine-dependent methyltransferase | Toxin YafO | ND | TraR homolog | Cro CI CII |
ND |
| vB_PaeS-D14E | 0 (4) | ND | DNA-cytosine methyltransferase (EC 2.1.1.37) | Toxin BrnT | ND | LuxR family protein | Cro CI |
ND |
| vB_PaeS-D14F | 1 (9) | ND | ND | ND | ND | ND | CII | ND |
| vB_PaeS-D14H | 0 (5) | ND | DNA-cytosine methyltransferase | YefM antitoxin YoeB toxin |
Holliday junction resolvase YqaJ-like exonuclease Restriction alleviation protein |
ND | Cro CI CII |
BCI PrtN |
| vB_PaeP-D14I | 0 (6) | ND | DNA methyltransferase C-5 cytosine-specific DNA methylase |
AbiEi antitoxin | Restriction alleviation protein | ND | CI LexA |
BCI |
| vB_PaeS-D14K | 0 (9) | ND | ND | ND | ND | ND | Cro/cI CII |
ND |
| vB_PaeS-D14L | 1 (4) | ND | ND | YafO family toxin | ND | LuxR family protein | Cro CI |
ND |
| vB_PaeS-D14O | 1 (17) | O-antigen acetylase Glycosyltransferase family 9 |
S-adenosyl-L-methionine-dependent methyltransferase | ND | ND | TraR homolog | Cro CI CII |
ND |
| vB_PaeS-D14P | 0 (8) | ND | ND | ND | Holliday junction resolvase | ND | Cro CI CII |
BCI |
| vB_PaeS-D14Q | 0 (3) | Glycosyltransferase family 9 | S-adenosyl-L-methionine-dependent methyltransferase | ND | ND | ND | ND | ND |
| vB_PaeP-D14S | 1 (6) | ND | Site-specific DNA-methyltransferase | AbiEi antitoxin | ND | ND | CI | BCI |
a
Acr: proven anti-CRISPR proteins. Numbers in brackets refer to putative Acr.
b
ND, not detected; QS, quorum sensing; TA, toxin/antitoxin.