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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Transfusion. 2023 May 29;63(7):1298–1309. doi: 10.1111/trf.17447

Table 1.

Patient baseline characteristics and clinical presentations following development of TACO.

Patient Characteristics Overall (n = 71)
Sex – n (%)
 Female – n (%) 40 (56.3)
 Male – n (%) 31 (43.7)
Race – n (%)
American Indian or Alaska Native 1 (1.4)
 Asian 19 (26.8)
 Black or African American 3 (4.2)
 White or Caucasian 33 (46.5)
 Other or Unknown 15 (21.1)
Age – median (IQR) 62.0 (51.0, 69.8)
 Age ≧ 65 years – n (%) 28 (39.4)
Any High Risk Comorbidities – n (%) 54 (76.1)
 Congestive Heart Failure 16 (22.5)
 Coagulopathy 47 (66.2)
 Renal Failure 18 (25.4)
 Organ Transplant 24 (33.8)
Blood Transfusion Product Type and Volume
 Multiple Blood Product Types – n (%) 49 (69.0)
  RBC + Platelets 31 (43.7)
  RBC + Platelets + Plasma 14 (19.7)
  Platelets + Plasma 2 (2.8)
  RBC + Plasma 1 (1.4)
  RBC + Platelets + Plasma + Cryoprecipitate 1 (1.4)
 Single Blood Product Type – n (%) 22 (31.0)
  RBC 14 (19.7)
  Platelets 6 (8.5)
  Plasma 2 (2.8)
 Transfusion Volume (mL) – median (IQR) 1262.5 (558.3, 2540.8)
 Transfusion Unit – median (IQR) 4.6 (2.0, 9.5)
TACO Management
 Any Fluid management - n (%) 63 (88.7)
 Bumetanide 4 (5.6)
 Furosemide 47 (66.2)
 Combination of pharmacological therapies 7 (9.9)
 Hemodialysis 7 (9.9)
 Any Oxygen Device – n (%) 57 (80.3)
  Oxygen Device FIO2 – median (IQR) 100 (100, 100)
  Ventilator – n (%) 8 (11.3)
Hospital Service
 General Surgery 3 (4.2)
 Hospital Medicine 13 (18.3)
 Liver Transplant 7 (9.9)
 Malignant Hematology 34 (47.9)
 Neurosurgery 5 (7.0)
 Other 9 (12.7)
Laboratory Measures – median (IQR)
 B-type natriuretic peptide (pg/mL) (n = 38) 396.0 (177, 1270.0)
 Systolic Blood Pressure (mmHg) 159.5 (141.8, 182.8)
 Diastolic Blood Pressure (mmHg) 81.0 (70.5, 94.8)
 Body Temperature (°F) 100.9 (99.3, 102.6)
 Body Temperature ≧ 100.4 °F – n (%) 41 (57.7)
 Chest X-Ray Radiology Score (n= 20) 3.0 (3.0, 3.0)
 Weight Changes (L) +1.35 (+0.2, +4.0)