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. 2022 Oct 8;26(3):543–551. doi: 10.1038/s41391-022-00599-2

Table 2.

Distribution of PI-RADS v2.1 scores, PSA densities, lesion sizes, zones, and locations within the prostate grouped by first MRI-targeted biopsy core revealing the most relevant histopathologic diagnosis.

1st biopsy core (n = 331) 2nd biopsy core (n = 66) 3rd biopsy core (n = 39) 4th biopsy core (n = 13) 5th biopsy core (n = 2) Overall (n = 451)
PI-RADS (PZ/TZ)
   score 2 28/16 2/0 0/0 0/0 0/0 30/16
   score 3 32/19 5/0 0/1 0/2 0/0 37/22
   score 4 97/16 22/3 16/3 8/0 1/1 144/23
   score 5 66/57 21/13 10/9 1/2 0/0 98/81
PSA density (ng/ml2) 0.20 ± 0.06 0.20 ± 0.04 0.21 ± 0.04 0.19 ± 0.06 0.20 ± 0.00 0.20 ± 0.05
Lesion size (mm) 15.6 ± 6.6 17.0 ± 8.2 16.1 ± 6.2 13.9 ± 8.2 11.8 ± 0.3 15.8 ± 6.8
Zone
   PZ 224 50 26 9 1 310
   TZ 107 16 13 4 1 141
Location
   apex 127 29 16 5 0 177
   midgland 126 26 17 6 1 176
   base 78 11 6 2 1 98

N number, ng nanogram, ml2 square milliliter, mm millimeter, PZ peripheral zone, TZ transition zone.