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. 2023 Aug 10;4:1214951. doi: 10.3389/falgy.2023.1214951

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© 2023 Cardenas, Cox, Willis-Owen, Moffatt, Cookson and Cooper.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Boxplots of OTU abundances of OTUs identified as significantly different by indicator species analysis and F-test are shown for subjects grouped by age and case/control status. Streptococcus_141 increased in cases compared to the control group at 7 months of age, and all others were decreased compared to that of the control group at the same age. *P < 0.00001.