FIG. 1.

Schematic of the first exon of the HIV-1 Tat protein. The amino acid changes are shown boxed below the native amino acid sequence. Multiple mutations are indicated by solid lines between boxed amino acids. The mutations in the tat gene product which were constructed are [E2G, D5G, E9G], P3L, P[6, 10]L, P[10, 14]L, C27S, K41A, and K/R[50-57]G.