Table 3.
Individual tumor and kidney AUC predictions versus observations for [177Lu]Lu-HA-DOTATATE, followed by calculated RPEs per patient (ID2–ID10)
| AUC0-tlast (mg*h/L) | ID2 | ID3 | ID4 | ID5 | ID6 | ID7 | ID8 | ID9 | ID10 |
|---|---|---|---|---|---|---|---|---|---|
| Tumor | |||||||||
| Observed | 3.32 | 2.09 | 5.29 | 4.69 | 1.38 | 2.80 | 2.94 | 1.76 | 2.59 |
| Predicted | 2.95 | 2.67 | 4.05 | 2.89 | 0.825 | 3.06 | 3.16 | 1.50 | 2.60 |
| RPE | −11% | 28% | −23% | −38% | −40% | 9% | 8% | −14% | 0% |
| Kidney | |||||||||
| Observed | – | 0.520 | 0.634 | 0.334 | 0.902 | 0.564 | 0.443 | 0.764 | 0.621 |
| Predicted | – | 0.533 | 0.680 | 0.469 | 0.408 | 0.479 | 0.410 | 0.496 | 0.426 |
| RPE | – | 4% | 14% | 41% | −53% | −12% | −10% | −32% | −32% |
AUC0-tlast, area under the curve, calculated from time is 0 to time of the last measurement; RPE, relative prediction error (((predicted – observed)/observed) * 100%)