Table 4.
Individual tumor and kidney absorbed dose predictions versus observations for [177Lu]Lu-HA-DOTATATE, followed by calculated RPEs per patient (ID2–ID10)
| Absorbed dose (Gy) | ID2 | ID3 | ID4 | ID5 | ID6 | ID7 | ID8 | ID9 | ID10 |
|---|---|---|---|---|---|---|---|---|---|
| Tumor | |||||||||
| Observed | 24.4 | 14.4 | 29.3 | 38.3 | 8.67 | 34.4 | 19.5 | 12.4 | 27.7 |
| Predicted | 21.3 | 17.4 | 19.6 | 18.7 | 5.62 | 25.5 | 28.1 | 12.1 | 21.5 |
| RPE | −13% | 21% | −33% | −51% | −35% | −26% | 44% | −3% | −23% |
| Kidney | |||||||||
| Observed | – | 3.12 | 2.21 | 1.19 | 5.38 | 3.92 | 3.79 | 4.41 | 3.71 |
| Predicted | – | 2.57 | 2.57 | 2.69 | 2.17 | 2.26 | 2.81 | 2.51 | 2.75 |
| RPE | – | 33% | −18% | 21% | 82% | −58% | −28% | −34% | −38% |
RPE, relative prediction error (((predicted – observed)/observed) * 100%)