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. 2023 Jul 13;129(5):772–781. doi: 10.1038/s41416-023-02331-w

Fig. 3. Immunohistochemistry showing expression of lymphocyte markers in primary uveal melanoma and uveal melanoma liver metastases.

Fig. 3

a Primary uveal melanoma. Moderate CD3 TILs (arrows) expression (red chromogen) (score = 2; 5–50%). b Uveal melanoma liver metastasis. Intense peri-tumoral CD3 infiltrate (arrowheads) (red chromogen) (score = 3; >50%) surrounds heavily pigmented metastasis. c Higher magnification of (b). Arrows highlight CD3+ peri-tumoral lymphocytes. d Uveal melanoma liver metastasis. Prominent peri-tumoral CD20 infiltrates (red chromogen). Inset (right lower) shows CD20+ lymphocytes.