Table 1.
Distribution of clinicopathological variables in a series of 28 primary uveal melanomas.
| Variable | Category | |
|---|---|---|
| Age | Mean (+/− SE) | 54.0 ( + /−2.3) |
| Gender | Female | N = 17 |
| Male | N = 11 | |
| Tumour diameter | Mean (+/− SE) | 16.6 ( + /− 0.5) |
| Histotype | Epithelioid | N = 14 |
| Spindle | N = 4 | |
| Mixed | N = 6 | |
| NA | N = 4 | |
| Local extension | Ciliary body | N = 8 |
| Optic nerve | N = 0 | |
| Scleral extension* | N = 2 | |
| None | N = 18 | |
| Melanin index | Mean (+/− SE) | 149.1 ( + /− 24.8) |
| HGP | Desmoplastic | N = 5 |
| Replacement | N = 17 | |
| NA | N = 6 | |
| aCGH status | D3/8 g | N = 4 |
| M3/8 g | N = 20 | |
| M3/8 N | N = 4 | |
| D3/8 N | N = 0 | |
| BAP1 loss | No | N = 8 |
| Yes | N = 17 | |
| NA | N = 3 | |
| Treatment | Enucleation | N = 23 |
| Proton | N = 5 | |
| Brachy | N = 0 | |
| Overall survival (months) | Median (95%CI) | 49.7 (34.7–NA) |
| Metastasis-specific overall survival | Median (95%CI) | 26.2 (16.3–82.5) |
*Angiotropism in sclera (2 cases), 1 case angiotropism and neurotropism.