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Percent of dose recovered in urine, feces, and dialysate after a single IV bolus of [14C]difelikefalin
| Group | Subject | Urine (%) | Feces (%) | Dialysate (%) | Total recovery (%) |
|---|---|---|---|---|---|
| Healthy subjects | n | 6 | 6 | – | 6 |
| Mean | 80.5 | 11.3 | – | 91.8 | |
| SD | 3.87 | 2.92 | – | 2.27 | |
| Subjects on hemodialysis | n | 3a | 6 | 6 | 6 |
| Mean | 11.2 | 58.8 | 19.5 | 83.8 | |
| SD | 3.43 | 6.14 | 7.47 | 1.78 |
IV intravenous
aNo urine was produced by three subjects on hemodialysis
