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. 2023 Jul 3;51(15):7762–7776. doi: 10.1093/nar/gkad566

Table 2.

Average FOSCTTM of algorithms for integrating GE and DM data

Cancer/Alg INTEND LIGER Seurat v3 MMD-MA MMD-MA WFCI (500) MMD-MA WFCI (2000) JLMA WFCI (500) JLMA WFCI (2000)
AML 2.42 (25) 29.83 (7) 17.05 (36) 23.63 (40) 19.08 (40) 22.35 (40) 24.01 (8) 28.38 (7)
BLCA 0.04 (39) 39.62 (9) 13.86 (40) 11.20 (40) 16.34 (40) 14.58 (40) 34.80 (40) 37.11 (40)
COAD 0.02 (37) 26.84 (19) 19.14 (40) 12.59 (40) 12.19 (40) 12.92 (40) 32.98 (5) 34.73 (4)
LGG 6.82 (22) 41.97 (8) 32.06 (26) 8.88 (40) 15.50 (40) 12.08 (40) 37.41 (14) 32.38 (12)
LIHC 0.14 (36) 42.34 (3) 19.23 (38) 16.04 (30) 11.02 (30) 12.94 (30) 32.68 (21) 36.03 (12)
LUAD 0.06 (32) 36.72 (4) 16.36 (39) 8.71 (40) 14.11 (40) 13.89 (40) 29.60 (9) 32.16 (8)
PAAD 0.55 (30) 36.68 (15) 24.18 (35) 11.07 (40) 23.42 (40) 16.27 (40) 29.83 (3) 27.44 (2)
PRAD 0.37 (38) 35.96 (8) 16.32 (17) 10.88 (40) 11.15 (40) 10.99 (40) 27.14 (2) 29.53 (2)
SARC 0.05 (35) 42.06 (15) 12.86 (36) 8.86 (40) 20.97 (40) 17.42 (40) 34.47 (7) 34.73 (5)
SKCM 0.03 (39) 42.20 (17) 18.97 (37) 16.02 (40) 20.53 (40) 16.62 (40) 32.11 (15) 34.71 (3)
THCA 3.07 (11) 32.58 (7) 15.96 (36) 6.71 (40) 7.78 (40) 6.65 (40) 30.95 (2) 27.52 (5)
Average (all datasets) 1.23 (31) 36.98 (10) 18.73 (34) 12.24 (39) 15.64 (39) 14.25 (39) 31.45 (11) 32.25 (9)

Average FOSCTTM score (percentge) for each algorithm on each of the 11 cancer datasets. The optimal score is 0%, and the expected score for a random projection is 50%. The requested shared space dimension d ranges from 2 to 40 for each algorithm. The score shown is the best across all values of d, and the optimal d is given in parentheses. The numbers 500 and 2000 for MMD-MA and JLMA denote the number of selected genes in the WFCI runs.